 If you have been researching how to improve your health, you may have heard of leaky gut, also known as intestinal permeability. If that conjures an unpleasant image of your gut contents leaking into the rest of your body — that’s not too far off the mark. Leaky gut happens when contents from the small intestine spill into the sterile bloodstream through a damaged and “leaky” gut wall. This contamination of the bloodstream by not only partially digested foods but also bacteria, yeast, and other pathogens begins to create a foundation for chronic inflammatory and autoimmune health disorders. Symptoms and disorders linked to leaky gut include fatigue, depression, brain fog, skin problems, joint pain, chronic pain, autoimmune disease, puffiness, anxiety, poor memory, asthma, food allergies and sensitivities, seasonal allergies, fungal infections, migraines, arthritis, PMS, and many more. Basically, your genetic predispositions will determine how leaky gut manifests for you. Leaky gut is referred to as intestinal permeability in the scientific research. It means inflammation has caused the inner lining of the small intestine to become damaged and overly porous. This allows overly large compounds into the small intestine. The immune system recognizes these compounds as hostile invaders that don’t belong in the bloodstream and launches an ongoing attack against them, raising inflammation throughout the body. Also, some of these compounds are very toxic (endotoxins) and take up residence throughout the body, triggering inflammation wherever they go. At the same time, excess intestinal mucous and inflammation from the damage prevents much smaller nutrients from getting into the bloodstream, which can lead to nutrient deficiencies and poor cellular function. Leaky gut is increasingly being recognized as a common underlying factor in most inflammatory symptoms and disorders. Medicine finally recognizes leaky gut Conventional medicine has long ridiculed leaky gut information and protocols as quack science and alternative medicine folklore, but newer research now establishes it as a legitimate mechanism. In fact, pharmaceutical companies are even working on drugs to address leaky gut. Research has established links between leaky gut and many chronic disorders. It’s good this long-known information is finally being validated in the dominant medical paradigm as the gut is the largest immune organ, powerfully influencing the rest of the body, as well as the brain. Current studies link intestinal permeability with inflammatory bowel disorders, gluten sensitivity, celiac disease, Crohn’s disease, type 1 diabetes, depression, psoriasis, and other chronic and autoimmune conditions. Given what we know about the connection between gut health and immunity, it’s vital to include a gut repair protocol in overall treatment of inflammatory and autoimmune disorders. How to mend leaky gut Sometimes, repairing leaky gut can be as simple as removing inflammatory foods from your diet. Other times it’s more complicated. Most importantly, you need to know why you have leaky gut. Either way, however, your diet is foundational. Many cases of leaky gut stem from a standard US diet of processed foods and excess sugars. Food intolerances also contribute significantly, especially a gluten intolerance. A leaky gut diet, also known as an autoimmune diet, has helped many people repair intestinal permeability. Keeping blood sugar balanced is also vital. If blood sugar that gets too low or too high, this promotes leaky gut. Stabilizing blood sugar requires eating regularly enough to avoid energy crashes. You also need to prevent high blood sugar by avoiding too many sugars and carbohydrates. Regular exercise is also vital to stabilizing blood sugar and promoting a healthy gut. Also, failure to eat enough fiber and produce leads to leaky gut by creating a very unhealthy gut microbiome, or gut bacteria. Our intestines (and entire body) depend on a healthy and diverse gut microbiome for proper function. A healthy gut microbiome comes from eating at least 25 grams of fiber a day and a wide and rotating variety of plant foods. Other common things that lead to leaky gut include antibiotics, NSAIDs such as ibuprofen, excess alcohol, hypothyroidism, and autoimmunity. A leaky gut protocol can help you improve your health, relieve symptoms, boost energy, make you happier, and clear your brain fog. Ask my office for advice on improving your well being through a leaky gut diet and protocol. Ask my office for more advice on managing autoimmunity or brain inflammation. Should you have any health questions please call the office at 317-848-6000. 
Although we start life with roughly 100 billion neurons, we start to lose neurons the moment we are born due to the effects of stress, toxins, inflammation, aging, trauma, disease, and other factors. So why can some people’s brains stay sharp and vital into old age? The answer is not in the number of neurons, but in neuroplasticity, the ability of your brain to learn and adapt to change by creating additional links to neighboring neurons. While strength in numbers is good, strength in connectivity is better when it comes to the brain. Each neuron can send out thousands of connections to other neurons. As we age, even though we lose many neurons and the ones we retain become slower, neuroplasticity means cells become better over time at making more connections. The resulting network of connection gives us the ability to complete complex tasks and even be that senior with a sharper mind than a PhD student. However, neuroplasticity depends on two main factors: stimulation and the right chemical environment. For example, a stroke patient who has smoked for 20 years (toxins and low oxygen), never exercises (low oxygen), and eats sweets and fast food every day (blood sugar issues) is going to have a different potential for recovery than someone who has a healthy diet, exercises regularly, and avoids environmental toxins. Their levels of plasticity are very different. One way to gauge your brain's potential for plasticity: Ask if it's easier to learn new facts or skills than it was five years ago. If it's easier, your brain has developed greater plasticity. If it's harder, you have inefficient plasticity. If you are in the second category, don't despair. Given the right tools and environment, your brain can improve its plasticity. How to support your brain's plasticity Our brains are incredibly adaptive, and given the right care — oxygen, fuel, and stimulation, they can stay healthy and sharp well into old age. Anti-inflammatory diet. A diet that supports stable blood sugar and addresses inflammation and food sensitivities is the foundation to restoring and supporting your brain's plasticity and health. Eat plenty of healthy fats. Our brains are composed largely of fats,and we need to eat plenty of healthy fats to support them. Focus on fats such as cold-water fish, olive oil, avocado oil, nuts, and coconut oil. Supplementing with omega 3 fatty acids is a great way to support brain health. Exercise daily. A body that moves has a brain that gets oxygen. Exercise also increases BDNF (brain derived neurotrophic factor), an anti-inflammatory brain chemical that helps eliminate brain fog and improve brain function. Stress reduction. Chronic stress causes a cascade of physiological effects that reduces oxygen and increases brain inflammation. Try these time-tested ways to reduce your daily stress level:
Prioritize sleep. Without adequate sleep, the brain and body experience increased inflammation and cannot function at their best. To improve sleep, adopt these daily habits:
Address food sensitivities. Food reactivity can cause systemic inflammation that leads to brain inflammation and degeneration. Ask your functional medicine practitioner for help in determining your sensitivities. Address hormonal imbalances. When hormones become imbalanced you lose neurotransmitter activity and brain function. PMS, perimenopause, menopause, and low or high estrogen in women as well as low testosterone in men can compromise brain health and function. Simple lab testing can help determine your next steps. Brain Based Exercises: My office specializes in prescribing specific brain based exercises to work on targeted areas of the brain we find to be under activated through our testing. Exercises to improve plasticity in networks of the brain can alleviate symptoms such as Migraine, Dizziness, Post Concussion Syndrome, ADHD and more. If exercises are performed 3-5 times a day for 3-6 months the brain can drastically improve over this short period of time. If you just don't feel like yourself, schedule a neurologic examination with us today! Contact my office for more information on how to improve yours.You can call us at 317-848-6000 or contact Dr. Ralston directly as drralston@neurohealthservices.com.  Obviously with the current pandemic of COVID-19, the novel coronavirus, I have been getting a lot of questions from patients regarding optimizing their immune system. So, we have been working with patients to help them understand their immune response and how to improve immune function so that the host, which is us, is less suitable for the COVID-19 virus. As you read in the paper and heard on the news reports, this is a new virus that mutated from animal species to a human virus and it is a new virus, therefore, our body does not have antibodies to this virus as of yet. The virus appears to be highly contagious and virulent to patients who are predisposed to immunocompromised, diabetes, obesity, inflammation, respiratory disorders, particularly targeting those over 60 years old. But for any patient to prevent illness and any one of us trying to ward off the effects of this virus, improving immune function is as important today as in the future. So, understanding your immune system, you basically have two players at hand with the immune system. We have the innate and the adaptive immune response. The innate immune response is basically the immediate immune response that would respond to a virus. The innate immune response is your stomach barriers, skin tissue, and your eosinophils, basophils, lymphocytes that would immediately come in contact with a potential pathogen such as a virus. The innate immune response can be influenced by anything that would stress your body, physical, chemical, psychological stress can all affect your innate immune response. Therefore, during this stressful time, trying to remain calm, trying to do things that are relaxing such as meditation, yoga, exercise, massage, even chiropractic to remove as much stress as possible. In regard to this virus, getting adequate sleep seems to be a definite important factor, especially for autoimmune patients who when their autoimmunity up regulates, their sleep/wake cycles become disrupted and their anxiety increases. Therefore, adequate sleep is probably paramount. And sadly, to say, when this quarantine happened, there is a lot more time to sit around and drink alcohol, but that is probably not a good strategy, trying to mildly to moderately consume alcohol would be a suggestion. Your adaptive immune system is more of your B and T cells. These are activated when the virus is in your body and the immune system is mounting an immune attack on the virus. Therefore, the role of the adaptive immune system is imperative as well. Some strategies we have been using nutritionally to support our patients, both innate and adaptive immune responses are products such as vitamin C. You have probably heard that vitamin C has been used in Shanghai and it has also been used in New York City intravenously. While vitamin C does not kill the virus, it certainly supports the immune system and decreases the effects of the virus on your system. Therefore, vitamin C seems to be a key influencer of the infection, so we are recommending our patients take vitamin C. You can take 1000 mg up to four times a day to bowel tolerance. Probiotics are also important. Probiotics support your gut barriers, as we talked about with the innate immune system. Taking probiotics is a key influencer of the immune system and, therefore, that is a good thing to add as well. Zinc, making sure your zinc levels are adequate is another important strategy. Optimum levels of Vitamin D are also important. Several studies have shown that low levels of Vitamin D make pt.’s susceptible to Covid. In my practice it is common to find pt.’s with low vitamin D levels especially bc of the long winters we have. Therefore, optimum levels of vitamin D are important now and moving forward. You can easily have your levels checked by your doctor; we are happy to provide this. Most pt.’s need on average 3-5K iu/day of vitamin daily just to maintain their levels through the winter. Specifically, in talking about COVID-19, it seems the pathological process is the cytokine storm that happens in the lung that creates significant breathing problems in patients who contract the virus. There are some studies that show that glutathione, which is an immune system booster, an antioxidant and an intracellular detoxifier downregulate cytokine load in the lung specifically. Therefore, I have been recommending my patients take Trizomal Glutathione, which is a product we carry. In addition, resveratrol, which is an antioxidant, has also been shown to be helpful with the effects of the virus, as well as some other Chinese herbs. Another important aspect in this managing stress. The fear and anxiety of this pandemic has been very high on some pt.’s. This stress response puts your body in fight or fight mode. As a result, cortisol, your stress hormone is increased. Cortisol weakens your immunes system, therefore managing stress is an important part of building your immunes system up. I use adrenal adaptogens to help manage cortisol and stress. Ashwagandha, Rhodiola are just a few of the compounds that I find helpful. If you find yourself really stressed, reach out to a provider for assistance. Therefore, in conclusion, if you should have any further questions about specific supplement strategies, you can feel free to contact my office at (317)848-6000. I think moving forward from this pandemic, one of the benefits may be an awakening of our need to prioritize our health and our immune system to make us as healthy and strong as possible. Monitoring your CBC, monitoring your white blood cell count and the factors of your immune system may be things that prove to be beneficial in the future rather than just looking at acute illness, looking at immune health on an ongoing basis. I hope everybody stays healthy. Sincerely, Brad Ralston  Concussions and Traumatic Brain Injuries (TBIs) are brain injuries that can alter brain functions short and/or long term. Brain injuries such as these are often hard to identify and treat, as structural damages are not normally present in brain imaging (MRI, CT). Despite this lack of visual damage to the brain, patients still often experience symptoms such as headaches, dizziness, confusion, fogginess, nausea, head pressure, memory-loss, and decreased brain function, among many others. For many people, concussions and other brain injuries are mild, and recovery takes only a short amount of time. However, for those who suffer from serious concussions and traumatic brain injuries, full recovery is very hard, if not impossible. The changes to the brain can have devastating and life-changing effects. Because of the complexity of concussions and traumatic brain injuries, recovery can be difficult, requiring highly specialized education and training. Additionally, no two brain injuries are alike, and effects of similar injuries can vary from person to person. In order to maximize potential of recovery, it is important for healthcare providers to identify the areas of decreased function and develop a personalized and strategic plan for each individual patient. Severe and even mild brain injuries can result in consequences to a person's life, impacting family, employment, and day to day social interactions. Without proper rehabilitation, individuals may be left in long-term injured states. However, long-term rehabilitation can help improve brain function and regain independence.  NeuroHealth Services aims to help patients restore and/or enhance brain function and independence using a specialized approach, suited to each individual patient. We utilize the following diagnostic equipment and rehab techniques:
Through in-office diagnostic testing, we identify brain impairments and dysfunction. We then develop a specific and individualized care program addressing any deficiency, carefully measure progress via re-examination, and modify treatment therapy based on patient progress. During intensive therapy, in-office rehabilitation can be complete in as little as one week. Interested in coming in?Visit our website for more information:
www.neurohealthservices.com/become-a-patient.html Or call our office to set up an appointment today at: 317-848-6000  When we think of concussions and brain injuries we tend to associate those with men, after all, they’re the ones playing football and predominantly in combat. But studies show both female athletes and women in general suffer a higher rate of concussions than men. Female brain injuries also tend to be more severe and require longer recovery. In fact, a recent study revealed that when it comes to high school athletes, female soccer players outrank male football players in incidences of traumatic brain injury. Almost 30 percent of injuries sustained by female players are brain injuries, whereas male football players have a much lower rate of brain injury at 24 percent. High school female athletes with concussions also reported more problems with sound and light sensitivity, nausea, dizziness, and drowsiness and took longer to recover. Professional female athletes also have significantly more brain injuries than their male counterparts in every sport except swimming and diving.
Why do women have more concussions? Although researchers don’t have definitive answers, looking at the structure of the female neck and head compared to the male can give us insight. The male neck is much stronger, bigger, and better able to handle acceleration than the female neck. When it comes to bone and neck strength, women are at a disadvantage when it comes to impacts, blows, and falls that affect the head and neck. Female hormones and brain injury Scientists have also found that female hormones appear to play a large role in brain injury risk. Female concussion risk and consequences are largely similar to male before puberty and after menopause. However, during the reproductive years, a woman’s menstrual cycle can affect how badly she is affected by a brain injury. For instance, women injured during the last two weeks of their cycle fare worse from a concussion than those injured during the first two weeks. Severity risk also appears to be tied to fluctuations in hormone levels throughout the cycle. The drops in estrogen during ovulation and menstruation trigger migraines in some women and may be periods of increased risk. Misconceptions around gender and concussions compound the problem. Many people still assume girls and women are at less risk for concussion and their symptoms go unreported simply due to lack of awareness. Pink Concussions is an organization dedicated to raising awareness and promoting research on concussions in women and girls. Functional medicine helps you recover from brain injury and concussion more quickly Functional Neurology excels in the field of brain recovery from concussions. In functional neurology we go beyond telling you to rest. A thorough functional neurology exam can pinpoint specific areas of injury to both the brain and the vestibular (inner ear) system. Different areas of the brain and the vestibular system require different rehabilitation strategies — customizing rehab to your areas of compromise will help you recover and improve faster. Plus, we look at functional medicine mechanisms in supporting your brain health. How is your hormone balance, your diet, and your gut health? Do you have chronic inflammation, food sensitivities, autoimmunity, or other unidentified stressors that could be making it harder for your brain to recover? These are important factors to address. You can call us at 317-848-6000 or contact Dr. Ralston directly as drralston@neurohealthservices.com. We offer a 10min consultation to discuss you condition and options to help.  Obviously with the current pandemic of COVID-19, the novel coronavirus, I have been getting a lot of questions from patients regarding optimizing their immune system. So, we have been working with patients to help them understand their immune response and how to improve immune function so that the host, which is us, is less suitable for the COVID-19 virus. As you read in the paper and heard on the news reports, this is a new virus that mutated from animal species to a human virus and it is a new virus, therefore, our body does not have antibodies to this virus as of yet. The virus appears to be highly contagious and virulent to patients who are predisposed to immunocompromised, diabetes, obesity, inflammation, respiratory disorders, particularly targeting those over 60 years old. But for any patient to prevent illness and any one of us trying to ward off the effects of this virus, improving immune function is as important today as in the future.
So, understanding your immune system, you basically have two players at hand with the immune system. We have the innate and the adaptive immune response. The innate immune response is basically the immediate immune response that would respond to a virus. The innate immune response is your stomach barriers, skin tissue, and your eosinophils, basophils, lymphocytes that would immediately come in contact with a potential pathogen such as a virus. The innate immune response can be influenced by anything that would stress your body, physical, chemical, psychological stress can all affect your innate immune response. Therefore, during this stressful time, trying to remain calm, trying to do things that are relaxing such as meditation, yoga, exercise, massage, even chiropractic to remove as much stress as possible. In regard to this virus, getting adequate sleep seems to be a definite important factor, especially for autoimmune patients who when their autoimmunity up regulates, their sleep/wake cycles become disrupted and their anxiety increases. Therefore, adequate sleep is probably paramount. And sadly, to say, when this quarantine happened, there is a lot more time to sit around and drink alcohol, but that is probably not a good strategy, trying to mildly to moderately consume alcohol would be a suggestion. Your adaptive immune system is more of your B and T cells. These are activated when the virus is in your body and the immune system is mounting an immune attack on the virus. Therefore, the role of the adaptive immune system is imperative as well. Some strategies we have been using nutritionally to support our patients, both innate and adaptive immune responses are products such as vitamin C. You have probably heard that vitamin C has been used in Shanghai and it has also been used in New York City intravenously. While vitamin C does not kill the virus, it certainly supports the immune system and decreases the effects of the virus on your system. Therefore, vitamin C seems to be a key influencer of the infection, so we are recommending our patients take vitamin C. You can take 1000 mg up to four times a day to bowel tolerance. Probiotics are also important. Probiotics support your gut barriers, as we talked about with the innate immune system. Taking probiotics is a key influencer of the immune system and, therefore, that is a good thing to add as well. Zinc, making sure your zinc levels are adequate is another important strategy. Optimum levels of Vitamin D are also important. Several studies have shown that low levels of Vitamin D make pt.’s susceptible to Covid. In my practice it is common to find pt.’s with low vitamin D levels especially bc of the long winters we have. Therefore, optimum levels of vitamin D are important now and moving forward. You can easily have your levels checked by your doctor; we are happy to provide this. Most pt.’s need on average 3-5K iu/day of vitamin daily just to maintain their levels through the winter. Specifically, in talking about COVID-19, it seems the pathological process is the cytokine storm that happens in the lung that creates significant breathing problems in patients who contract the virus. There are some studies that show that glutathione, which is an immune system booster, an antioxidant and an intracellular detoxifier downregulate cytokine load in the lung specifically. Therefore, I have been recommending my patients take Trizomal Glutathione, which is a product we carry. In addition, resveratrol, which is an antioxidant, has also been shown to be helpful with the effects of the virus, as well as some other Chinese herbs. Another important aspect in this managing stress. The fear and anxiety of this pandemic has been very high on some pt.’s. This stress response puts your body in fight or fight mode. As a result, cortisol, your stress hormone is increased. Cortisol weakens your immunes system, therefore managing stress is an important part of building your immunes system up. I use adrenal adaptogens to help manage cortisol and stress. Ashwagandha, Rhodiola are just a few of the compounds that I find helpful. If you find yourself really stressed, reach out to a provider for assistance. Therefore, in conclusion, if you should have any further questions about specific supplement strategies, you can feel free to contact my office at 317-848-6000. I think moving forward from this pandemic, one of the benefits may be an awakening of our need to prioritize our health and our immune system to make us as healthy and strong as possible. Monitoring your CBC, monitoring your white blood cell count and the factors of your immune system may be things that prove to be beneficial in the future rather than just looking at acute illness, looking at immune health on an ongoing basis. I hope everybody stays healthy. Sincerely, Dr. Ralston  The study’s authors remind us that nothing in the body acts in isolation, something we’ve long known in functional medicine and functional neurology. Understanding some brain basics helps you understand symptoms when your brain isn’t working right. The brain is our heaviest and most complex organ, using most of the body’s oxygen and about 30 percent of its energy supply. The brain is divided into sections, each in charge of different functions although all working together. In functional neurology, we can identify areas of poor brain function and help you get them working better again with customized therapy and rehabilitation. Frontal Lobe The frontal lobe is the area of your forehead that stretches between the temples. The human frontal lobe distinguishes us from other animals and governs much of our personality, impulse control, and the ability to reason. A frontal lobe injury can completely change your personality and ADHD is understood to affect the frontal lobe. The frontal lobe also governs emotional drive, motivation, and planning. Poor frontal lobe function can result in an inability to set goals or follow through on projects or plans. You may feel lazy, unmotivated, or depressed if so. In fact, depression is simply a frontal lobe impairment. The frontal lobe activates the muscles. Poor frontal lobe function can result in moving more slowly or not swinging your arms when you walk. Fine-motor coordination also falls under the frontal lobe’s duties. This is needed for handwriting, embroidery, and other detailed movements of the hands. As the frontal lobe degenerates it’s typical for handwriting to worsen. Symptoms and signs of possible frontal lobe impairment
Temporal Lobe The temporal lobes are located on either side of the brain above the ears. They govern hearing, speech, memory, emotions, and distinguishing smells. Tinnitus (ringing in the ear) is a common symptom of temporal lobe dysfunction, although not all tinnitus is due to temporal lobe degeneration, as is difficulty distinguishing between different tones. Within the temporal lobes is the hippocampus, the seat of learning and memory. Degeneration of the hippocampus leads to poor memory and eventually Alzheimer’s disease. It is also involved with spatial orientation, sense of direction, and circadian rhythm (sleep-wake cycle). Symptoms and signs of possible temporal lobe impairment
Parietal Lobe The parietal lobes are located behind the ears and perceive and interpret sensations such as touch, pressure, texture, weight, size, or shape. The parietal lobe function also tells the body where it is in its environment. Reoccurring injuries are common with parietal lobe impairment. Symptoms and signs of possible parietal lobe impairment
Cerebellum Your cerebellum is two lobes at the back of the head, directly above your neck. It calibrates muscle coordination and balance and filters information before sending it to the brain. Symptoms and signs of possible cerebellum impairment
Occipital Lobe The occipital lobe is in the back of the brain and processes visual information. Symptoms of possible occipital lobe impairment
Any of the above symptoms in adults usually mean degeneration in those areas of the brain while in children it can signal poor brain development. If your overall brain function is declining, you may have many of these symptoms.
The good news is the brain is very receptive to improving with the right nutrients and input. Functional neurology excels in identifying areas of brain dysfunction and customizing brain rehabilitation specifically for your brain. Ask my office for more information on a 10 min diagnostic exam to evaluate your brain function for only $69.00. You can contact our office at 317-848-6000 or contact Dr. Ralston directly at drralston@neurohealthservices.com. How you were born could shape the rest of your life thanks to the effects of bacteria at birth.1/2/2020
Whether you’re fat or thin, anxious or relaxed, sickly or resilient — this could all stem from the way you were born thanks to the effects of bacteria in our first few seconds of life. Babies born via c-section are shown to have less desirable gut bacteria, or a gut microbiome, compared to babies born vaginally, who have healthier microbiome “signatures.”
Results from the largest study of the newborn microbiome were recently published. The study found that newborns delivered via c-section lack the healthy gut bacteria found in vaginally delivered babies. Their guts also contain strains of harmful microbes — Enterococcus and Klebsiella — commonly found in hospitals. In fact, the lead researcher said the levels of harmful hospital bacteria in the c-section newborns was “shocking.” These babies were also deficient in the healthy bacteria that made up most of the guts of the vaginally born babies. The difference was so profound that he said he can tell you how the baby was born simply by analyzing the bacteria in their stool. C-section babies missing strain vital for health, weight management, and immune resilience After several months the gut microbiomes between the two set of infants became more similar with one striking difference — the c-section babies had significantly lower levels of Bacteroides, a strain vital to human health. Bacteroides are a key strain when it comes to health challenges modern societies face. A number of studies have shown Bacteroides levels are lower in people with obesity. Studies in both mice and humans show that when gut bacteria from thin subjects are transplanted into the colons of obese subjects, most subjects lose weight. Bacteroides has also been linked with preventing anxiety, and boosting and regulating immunity to prevent inflammatory disorders. This may explain why people who were born via c-section are at increased risk for obesity and asthma. The study is part of a larger Baby Biome study that is following thousands of newborns through childhood. Why method of birth affects the gut microbiome Research suggests that the vaginal canal imparts beneficial bacteria to the infant during birth, while c-section babies are deprived of that and instead immediately exposed to the bacteria of the hospital and the people attending the birth. Studies are underway in which babies born via c-section are swabbed with the mother’s vaginal microbes. Other factors to consider beyond birth It may not just be the birth that determines a c-section baby’s poorer microbiome status. Women who undergo c-sections also receive antibiotics, which may transfer to the newborn through the placenta and later through breast milk. These babies also tend to stay in the hospital longer and thus are exposed to more hospital bacteria. How to develop healthy gut bacteria Developing good gut bacteria is not necessarily as simple as taking probiotics. You may also be overrun with detrimental bacteria that need to be “weeded.” Perhaps most important is whether your diet supports a healthy gut microbiome. What the gut microbiome needs most is an ample supply of vegetables and fruits on a regular basis in a wide, ever changing variety. Eating a diverse and abundant array of plant foods will help create a diverse and abundant gut microbiome. Ask my office for more advice on how we can help you improve your gut microbiome and overall health. Should you have any health questions please call the office at 317-848-6000. If there were just one magic bullet to feel and function better, it would probably be exercise. Countless studies show the numerous benefits of exercise. Our bodies and brain were designed for constant physical activity and perform at their best when we provide that. Exercise releases chemicals that boost your overall energy and dampen inflammation.
But what to do if exercise actually makes you feel worse? Some people battling autoimmunity or brain inflammation suffer from exercise intolerance and see their symptoms worsen after physical activity. Many autoimmune and brain inflammation patients see multiple doctors before receiving a diagnosis. Most of these doctors will tell a severely compromised patient they just need to exercise more. This advice can actually worsen a patient’s symptoms until they start bringing their inflammation under control. What is exercise intolerance? In the conventional medical model, exercise intolerance is most often associated with heart disease, particularly from the heart not filling adequately with blood. As a result, insufficient blood is pumped out to the rest of the body. However, in functional medicine we frequently see exercise intolerance in people struggling with autoimmunity and brain inflammation. It’s normal to feel sore or tired after a tough workout, but people who suffer from exercise intolerance experience more severe and unusual pain, fatigue, a flare up of their autoimmune symptoms, nausea, vomiting, or other negative effects that go beyond normal muscle tiredness. Some “crash” for a day or more with flu-like symptoms, feeling unable to get out of bed or function normally. Exercise intolerance can be very emotionally distressing for people who care about their health and are working to improve it. After all, we are constantly bombarded with images of uber athletes and messaging about intense workouts. What causes exercise intolerance? When exercise intolerance is related to autoimmunity or brain inflammation, exercise intolerance is a result of compromised mitochondria. Mitochondria are known as the “energy factories” inside each cell, as their role is to take nutrients and oxygen and turn that into energy. Unfortunately, mitochondria are also very sensitive to inflammation and will under function when the body is struggling with intense inflammation. This means the cells don’t function well, the brain under functions, and you generally feel crappy and fatigued. How to exercise if you have exercise intolerance? One of the most common mistakes people make is to push themselves too hard and over exercise. Over training spikes inflammation and can make an autoimmune or brain inflammation condition worse. Also, when you have an inflammatory condition, you must realize your immune system is never at a constant. Stress, viruses, diet, and myriad other factors keep our immune systems in a constant state of fluctuation. People with autoimmunity or brain inflammation must always tweak and adjust their activity level to not overburden their immune system or neurological health. If you are used to working out a certain level and then suddenly notice your workout make you feel worse, it could be an outside factor flaring up inflammation. So you need to dial it down or even take some time off. Listen to your body. For instance, someone who does high-intensity interval (HIIT) and weight training four or five days a week suddenly feels fatigued and lethargic the day after each class. They may need to reduce the duration, the intensity, or the frequency of those workouts, or substitute in something that doesn’t push their inflammation over the edge, like a brisk walk. Forget about cultural messaging around fitness Managing autoimmunity and brain inflammation is highly individualized; no two people will have the same protocol. You must always be tuned in to what your body says. This can be difficult in our hyped-out fitness culture. After all, for some autoimmune or brain inflammation folks, the mildest workouts can be triggering. The goal is to find what works for you and makes you feel good. When we stimulate blood flow through movement, it sends more oxygenation to our bodies and brains and triggers the release of beneficial chemicals. If it feels good, it’s lowering inflammation and helping you manage your autoimmunity and brain inflammation. Autoimmune appropriate exercises for building exercise tolerance could be walks, light weight training, gentle yoga or stretching routines, water aerobics — explore and find what works for you. You are the ultimate expert on what’s right for your body. As you start to feel better you will naturally feel inclined to take on more. Start low and slow so that you are able to stay consistent and keep it up on a daily basis. Once you have established that, then gradually increase intensity and duration. Ask my office for more advice on managing autoimmunity or brain inflammation. Should you have any health questions please call the office at 317-848-6000. What is MTHFR and why should you care when you have Hashimoto’s hypothyroidism or brain issues?11/14/2019
Have you been googling for ways to improve your hypothyroid or brain condition and come across suggestions to test MTHFR? What is MTHFR and what does it have to do with hypothyroidism or the brain? If you are one of the 60 percent of people with a genetic defect in the MTHFR gene, it could affect your ability to successfully manage Hashimoto’s hypothyroidism or brain-based symptoms.
MTHFR is the acronym for methylenetetrahydrofolate reductase, an enzyme involved in processing folate, or vitamin B9, into a usable form the body can assimilate. It’s also necessary to metabolize folic acid, a synthetic form of folate used in supplements. Thanks to the popularity of gene testing, people can now learn whether they have a mutation in the MTHFR gene. If so, it means their methylation pathways are impacted and contributing to health challenges. Methylation pathways govern detoxification and many important metabolic processes in the body, which makes a MTHFR defect something worth paying attention to. If you are struggling to manage your Hashimoto's hypothyroidism or brain-based symptoms such as brain fog, fatigue, or depression, you may find the MTHFR test valuable. Methylation is a process of adding a methyl group to a molecule. Methylation’s roles jobs include the following:
Proper methylation means one can efficiently make proteins, use antioxidants, metabolize hormones, enjoy more balanced brain chemistry, detoxify toxins and heavy metals, and dampen inflammation. All of these factors are vital to managing Hashimoto's hypothyroidism and brain-based symptoms. However, if you’re one of the 60 percent of people with a MTHFR genetic defect, you may not be able to properly break down folate in foods or folic acid in supplements. An inability to properly process folate can raise levels of homocysteine. Homocysteine is an amino acid in the bloodstream that can be dangerous when levels are too high. High homocysteine is linked to an elevated risk of heart disease and Alzheimer’s. Poor methylation also impacts another vital process — the production of glutathione, the body’s main antioxidant. When we become deficient in glutathione, we lose our natural defenses and are at higher risk of developing autoimmune diseases, food sensitivities, and chemical sensitivities. An MTHFR defect can also impair the body’s ability to synthesize important brain neurotransmitters, so that brain-based disorders may arise. An MTHFR defect has been linked to depression, anxiety, brain fog, ADHD, bipolar disorder, and even schizophrenia. Because methylation is involved in so many important processes in the body, an MTHFR gene defect has been associated with many health conditions, including:
If you are trying to manage a condition like Hashimoto's hypothyroidism or brain-based symptoms, it’s imperative that you be able to dampen inflammation and raise glutathione levels. An MTHFR defect can work against you. Fortunately, it can be easy to address. First of all, you can test for MTHFR gene mutations through genetic testing companies such as Spectracell or 23andme.com, and get an interpretation at geneticgenie.org. More than 50 MTHFR genetic mutations exist, but the two considered the most problematic are C677T and A1298C (written as just 677 and 1298). Also, keep in mind gene defects don’t always become activated. If you show those genes on a test it doesn’t necessarily mean they have been expressed and are causing symptoms. To address a MTHFR enzyme defect, support your methylation pathways with methylfolate and methylcobalamin (methyl B12). Avoid supplements with folic acid, boost your glutathione levels with high quality oral liposomal glutathione, and minimize your exposure to toxins. These are also beneficial strategies to aid in the management of Hashimoto's hypothyroidism and brain-based symptoms. Ask my office for more advice on managing autoimmunity or brain inflammation. Should you have any health questions please call the office at 317-848-60 |
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